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Vol. 16, Art. 48 (pp. 507-521)    |    2015       

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Hemostasis by nonequilibrium plasma during spleen surgery

Semichev E.V., Siberian State Medical University
Baykov A.N., Siberian State Medical University
Shevtsova N.M., Siberian State Medical University
Bushlanov P.S., Siberian State Medical University
Gereng E.A., Siberian State Medical University
Koshhevets E.S., Siberian State Medical University
Aleynik A.N., National Research Tomsk Polytechnic University

Brief summary

The relevance of research related to the problem of excessive bleeding after spleen injury and the lack of available methods of hemostasis. The paper presents results of research of nonequilibrium plasma influence on spleen tissue after coagulation. The study was performed on rabbits. Biochemical values, clinical blood analysis, histological data were assessed at different periods (3rd, 5th, 7th, 14th and 30th days) after surgery with nonequilibrium plasma coagulation. Nonequilibrium plasma hemostasis leads to reduction of the specific volume of white and red pulp in early postoperative period. Changes of biochemical values and clinical blood analysis indicate increase in total body responsiveness after surgery. This results and the absence of lethal outcomes among the experimental animals allow to recommend the use of nonequilibrium plasma coagulator for spleen hemostasis.


Key words

haemostasis of parenchymal organs, nonequilibrium plasma, surgery of parenchymal organs, spleen trauma

Reference list

1. Aleinik A.N., Deneko O.I. Plazmennaya medicina : Ychebnoe posobie. Tomsk : TPY. 2011; 17.


2. Popov V.A. Gemostaz i germetizaciya shvov (operacii na vnytrennih organah). M.: GEOTAR-Media 2008; 320.


3. Savelev V.S., Kirienko A.I. Klinicheskaya hiryrgiya : nacionalnoe rykovodstvo : v 3 t. M.: GEOTAR-Media 2009; T. II; 401.


4. Borodin O.U., Semichev E.V. Analiz kontrastiryushego effekta pri dinamicheskoi magnitnorezonansnoi tomografii s Primovistom y kris, operirovannih na pecheni s primeneniem klassicheskogo shva. Medicinskaya vizyalizaciya. 2012; №4; 118-125.


5. Borodin O.U., Semichev E.V. Morfofynkcionalnaya harakteristika pecheni posle gemostaza neravnovesnoi plazmoi na otdalennie sroki v ysloviyah eksperimenta. Bulleten sibirskoi medicini. 2012; №6; 21-31


6. Borodin O.U., Semichev E.V., Byshlanov P.S. Eksperimentalnaya hiryrgiya parenhimatoznih organov (obzor literatyri). Rysskii medicinskii jyrnal Hiryrgiya. Yrologiya. 2012; № 36; 1743.


7. Ahmed N., Vernick J.J. Management of liver trauma in adults. // J Emerg Trauma Shock. 2011. Vol. 4 (1). P. 114–119.


8. Alkozai E.M., Lisman T., Porte R.J. Bleeding in liver surgery: prevention and treatment. // Clin Liver Dis. 2009. Vol. 13 (1). P. 145-154.


9. Carus T, Rackebrandt K. Collateral tissue damage by several types of coagulation (monopolar, bipolar, cold plasma and ultrasonic) in a minimally invasive, perfused liver model. // International Scholarly Research Network ISRN Surg. 2011. Vol. 2011 P. 1


10. Fridman G., Peddinghaus M., Ayan H., Fridman A., Balasubramanian M., Gutsol A., Brooks A. Friedman G. Blood Coagulation and Living Tissue Sterilization by Floa-ting-Electrode Dielectric Barrier Discharge in Air. Plasma Chem. Plasma Process. 2006, V. 26; p.425-442.


11. Fridman G., Peddinghaus M., Fridman A., Balasubramanian M., Gutso A.l, Friedman G. Use of non-thermal atmospheric pressure plasma discharge for coagulation and sterilization of surface wounds. 17th international Symposium on plasma chemistry. Toronto, 2005, p. 1-2.


12. Sameer U. Kalghatgi, Gregory Fridman, Moogega Cooper, Gayathri Nagaraj, Marie Peddinghaus, Manjula Balasubramanian, Victor N. Vasilets, Alexander F. Gutsol, Alexander Fridman, and Gary Friedman. Mechanism of Blood Coagulation by Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge. Plasma Science. 2007. ICOPS 2007. IEEE 34th International Conference. 2007, p. 674.


13. Sameer Kalghatgi1, Crystal M. Kelly, Ekaterina Cerchar, Behzad Torabi, Oleg Alekseev, Alexander Fridman, Gary Friedman, Jane Azizkhan-Clifford. Effects of Non-Thermal Plasma on Mammalian Cells. PLoS ONE. 2011; 6(1): e16217. DOI: 10.1371/journal.pone.0016270. PMID: 21283714


14. Airazat M. Kazaryan, Joachim Wiborg, Kristin Hauss, Tommy K. Anundsen, Olav J. Flemmen, Thor Erik Holm, Giedrius Lauzikas. Spontaneous non-traumatic massive intraabdominal spleen bleeding in young females: Importance of ATLS principles and trauma alarm. Am J Case Rep. 2014 May 5; 15:189-93.


15. Daniel Murariu, Sarah Takekawa, and Nancy Furumoto. Splenic Rupture: A Case of Massive Hemoperitoneum Following Therapeutic Colonoscopy. Hawaii Med J. Jun 2010; 69(6): 140–141.

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