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Медико-биологический
информационный портал
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Vol. 16, Art. 33 (pp. 350-356) | 2015
Metal-affinity chromatography as a method specificity extraction of harmful chemicals and their derivatives from environmental objects and biological solution
Shreyner E.V., Gladilovich V.D., Keltcieva O.A., Kolonitskyi P.D., Efremov T.A.,
Strukov M.K., Alexandrova M.L., Selutin A.A., Suhodolov N.G., Podolskya E.P. Federal State Institution of Science "Institute of Toxicology, Federal Medical-Biological Agency" Institute for Analytical Instrumentation RAS St. Petersburg State University
Brief summary
The work is devoted to research the possibility of using metal-affinity chromatography for specific extraction of glyphosate, aminomethylphosphonic acid, pirimicarb, fenazepama from aqueous solutions and blood plasma of rats. In work we have used the previously developed two types of metal-affinity sorbents based on Langmuir-Blodgett films and nanosized oxide containing ions of Fe (III), Cu (II), Ni (II). It is shown that this method allows efficient sample preparation in quantitative analysis of water-soluble toxic substances with active functional groups. Key words metal-affinity hrogmatografiya, Langmuir-Blodgett films, nanosized oxide, toxic substances. (The article in PDF format. For preview need Adobe Acrobat Reader)  Open article in new window
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