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Vol. 22, Art. 34 (pp. 498-506)    |    2021       

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Indicators of myoelectric activity of gastrointestinal tract in victims with severe combined shockogenic trauma and methods of their correction

Sadulaev D.Sh., Barsukova I.M., Makhnovskiy A.I., , Dubikaitis1 P.A., Sizonenko N.A.

1Sankt- St. Petersburg Research Institute of Ambulance named after I.I. Dzhanelidze
2First St. Petersburg State Medical University named after academician I.P. Pavlov
3Military Medical Academy named after S.M. Kirova

Brief summary

Trauma is the leading cause of death among young people. The aim of the study is to improve the results of treatment of victims with severe combined shockogenic injury, taking into account disorders of myoelectric activity of the gastrointestinal tract, using methods of their pathogenetic drug correction using early enteral infusions and substrate antihypoxant (Cytoflavin). Clinical, laboratory and instrumental (electrogastroenterography), statistical and analytical research methods were used, among the therapeutic measures for the study, early enteral infusions, intravenous and enteral administration of Cytoflavin are significant. It was found that in severe combined shockogenic injury, there is a violation of the myoelectric activity of the gastrointestinal tract, manifested by a decrease in its total electric power with an increase in the frequency of contractions. Low values of total electric activity power of gastrointestinal tract and growth of rhythmicity coefficient of all its sections on the 5th day of early post-traumatic period of traumatic disease course are prognostic unfavorable signs. The use of the substrate antihypoxant Cytoflavin normalizes the indicators of myoelectric activity of the gastrointestinal tract (eliminates the imbalance in relative power between the overlying (stomach, small intestine) and the underlying parts (large intestine), eliminates discordant contractions of the jejunum and ileum). Its introduction in combination with early enteral infusions in the complex of therapeutic measures for severe combined shockogenic injury is accompanied by a reduction in the length of stay of the victims in the hospital (by 5.6 ? 4.0 bed-day) (p < 0.05).


Key words

severe combined trauma, shock, myoelectric activity of the gastrointestinal tract, Cytoflavin

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