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Институт теоретической и экспериментальной биофизики Российской академии наук.

ООО "ИЦ КОМКОН".




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199406, Санкт-Петербург, ул.Гаванская, д. 49, корп.2

ISSN 1999-6314

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«
Vol. 20, Art. 10 (pp. 94-109)    |    2019       
»

Short- and long-term bleeding complications after percutaneus coronary intervention in long-lived persons with acute coronary syndrome
Kurnikova E. A.1,2, Shenderov S. V.1, Dorofeev V. I. 1, Filippova O.I.1

1 City hospital 26, 2 Kostyushko str., Saint-Petersburg, 196247, Russian Federation, Tel.: +7(812)415-18-88; E-mail: b26@zdrav.spb.ru
2 Saint-Petersburg State Pediatric Medical University, 2 Litovskaya str, Saint-Petersburg, 194100, Russian Federation



Brief summary

Background. Bleeding is the widespread noncardiac complication after percutaneus coronary intervention. The aim this examination include the investigation of frequency and prediction capability hemorrhagic complications in short- end long-term time after percutaneus coronary intervention in long-lived patients with acute coronary syndrome Material and methods. This investigation includes retrospective analysis effect management of treatment acute coronary syndrome (PTCA vs conservative therapy) on frequency, time of development different types of bleeding complication in long-lived patients with acute coronary syndrome. Results. Short- end long-term bleeding are frequent complications in among long-lived patients with acute coronary syndrome undergoing primary percutaneous coronary intervention. The most patients experienced a BARC type ≤2 bleeding. The bleeding development et short-term period was connected with severity of acute heart failure (Killip III, IV), exertion fraction of left ventricle less than 40%, admission aPTT, pretreatment NOAC. Et long-term period diabetes mellitus and treatment by non-steroidal anti-inflammatory agent more than 5 days are associated with increasing the frequency of bleeding. The ACTION-GWTG is the most conclusive prognostic scale of bleeding in long-lived patients with acute coronary syndrome undergoing primary percutaneous coronary intervention. Conclusion. Our examination demonstrates not only the need for a more searching study of the predictors of bleeding in long-lived patients with acute coronary syndrome, but also the development of a specific prognostic risk score scale of hemorrhagic complications, adapted for patients of this age group.


Key words

hemorrhagic complication; percutaneous coronary intervention; acute coronary syndrome; long-lived patients





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