The increase of aggregative functions of thrombocytes in vitro and in vivo was revealed in new-born calves with risk dyspepsia. Profound displacements are in the base of the disturbances of lipid composition of thrombocyte membranes, the increase of the level of the middle molecules and activation of peroxide oxidation of lipids in plasma and in platelets, strengthening of Willebrand factor synthesis in the wall of vessels and intensification of thromboxan formation in platelets. Correction of thrombocyte ling hemostasis. Is possible with the help of pathogenous stipulating complex of phosphopag, acos and calcium gluconate capable to decrease the level of middle molecules in organism and to correct peoxide oxidation of lipids.
2. Gabrielyan N.I., Lipatova V.I. i dr. Skriningovii metod opredeleniya srednih molekyl v biologicheskih jidkostyah. Metodicheskie rekomendacii. M.1985.
3. Kybatiev A.A., Andreev S.V. Perekisi lipidov i tromboz. // Bull. eksperim. biol. i medicini. 1979.-№ 5.-s. 414-417.
4. Naymov M.M., Medvedev I.N., Efimov K.M. i dr. Prakticheskie rekomendacii po primeneniu «Biopaga-D» v veterinarii. Moskva, 2006.
5. Shitikova A.S., Tarkovskaya L.R., Kargin V.D. Metod opredeleniya vnytrisosydistoi aktivacii trombocitov i ego znachenie v klinicheskoi praktike. //Klinich. i labor. diagnostika. 1997.-№ 2.-s. 23-35.
6. Shitikova A.S. Vizyalnii mikrometod issledovaniya agregacii trombocitov. V kn. Gemostaz. Fiziologicheskie mehanizmi, principi diagnostiki osnovnih form gemorragicheskih zabolevanii. Pod red. N.N. Petrisheva, L.P. Papayan. SPb, 1999.-s.49-53.
7. Schmith J.B., Ingerman C.M., Silver M.J. Malondialdehyde formation as an indicator of prostaglandin production by human platelet. //J.Lab. Clin. Med. 1976.-Vol. 88 (1).-p.167-172.