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Vol. 24, Art. 10 (pp. 121-127)    |    2023       

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Software for individual evaluation of fibrinolytic volume in the treatment of subretinal hemorrhages

Fayzrakhmanov R.R., Вosov E.D., Bogdanova V.A., Tumanov I.I., Karpov G.O.

N.I. Pirogov National Medical Surgical Center
Institute of Advanced Training of Physicians N.I. Pirogov National Medical Surgical Center
LTD «KB Rus»

Brief summary

Purpose of the study. Development and clinical application of software for individual calculation of the volume of fibrinolytic infusion solution for surgical treatment of submacular hemorrhages. Material and methods. Based on the processing of optical coherence tomography data using three-dimensional visualization, the program "3D volume calculator" was developed. As a vitreoretinal intervention, a two-port 27G surgery was performed with controlled subretinal administration of a calculated recombinant prourokinase solution through a 38G cannula and hexafluoroethane tamponade at 20% of the volume of the vitreal cavity. Results. The developed program makes it possible to measure the volume of submacular hemorrhage, and also calculates an individualized amount of subretinal infusion solution for reliable displacement of the blood clot to the periphery. 2 weeks after surgery for submacular hemorrhage, complete dislocation was observed in 40 cases (93%). Conclusion. To date, minimally invasive surgery and a personalized approach are the fundamental directions in modern ophthalmology. The application of the proposed program in clinical practice has proven its effectiveness in relation to morphological and functional perspectives in the treatment of submacular hemorrhages.


Key words

submacular hemorrhage, software, calculation of fibrinolytic volume, minimally invasive surgery

Reference list

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