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Vol. 22, Art. 46 (pp. 650-665)    |    2021       

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A rare case of massive extracranial metastasis of gliosarcoma

Vorobieva O.M., Ryzhkova D.V., Sulin K.A.,Grishina A.R., Sidorin V.S., Danilova I.A., Gulyaev D.A., Mitrofanova L.B.

«Almazov National Medical Research Center»

Brief summary

A clinical case of extracranial metastasis of gliosarcoma with lipomatous differentiation in a 53-year-old man is described. Initially, glioblastoma of the right parietal lobe was diagnosed, and surgical treatment was performed. After 4 months, a transformation into gliosarcoma was revealed, and a second operation was performed. Another 5 months later revealed multiple secondary changes in the lungs, liver, spleen, mediastinal lymphadenopathy, bilateral hydrothorax and destruction of the left VII rib. After another 2 weeks, the patient died of intoxication. Autopsy diagnosed gliosarcoma with multiple extracranial metastases. The article provides an analysis of literature data.


Key words

glioblastoma, secondary gliosarcoma, extracranial metastasis

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