Опубликовать статью

Информационное партнерство

Инфоресурсы

Контакты

«

Vol. 21, Art. 44 (pp. 550-560)    |    2020       

»

Primary response of the afferent neuron to acute radiation exposure and alcohol intoxication.

1Voronezh State Institute of Physical Training (Karl Marks Str., 59, Voronezh, 394036, Russia)
2State Research Center - Burnasyan Federal Medical Biophysical Center
(Zhivopisnaya Str., 46, Moscow, 123182, Russia)
3Nikiforov Russian Center of Emergency and Radiation Medicine, EMERCOM of Russia (Academica Lebedeva Str., 4/2, St. Petersburg, 194044, Russia)
4Military Training and Scientific Center of the Air Force "Air Force Academy named after Professor N.E. Zhukovsky and Yu.A. Gagarin"
(Old Bolsheviks Str., 54 A, Voronezh, 394064)

Brief summary

The study evaluated the primary response of the afferent neuron of the trigeminal node to acute radiation exposure in a cerebral dose and a toxic dose of ethanol. It is shown that these factors cause early observations of significant changes in the structural and functional organization of sensitive nerve cells, and their primary reaction is probably not decisive in the development of cerebral disorders under the influence of the studied factors. At the same time, more heterochronous and heteromorphic changes were observed with the introduction of ethanol than with radiation exposure, which does not allow us to confirm the syndrome of the studied factors by the primary reaction of the afferent neuron.


Key words

experiment, rats, neuron, acute alcohol intoxication, acute radiation exposure.

Reference list

Byrov U.V., Vedernikov N.N. Neirohimiya i farmakologiya alkogolizma. M.: Medicina, 1985. 240 s.


2.Davidov B.I., Yshakov I.B. Ioniziryushie izlycheniya i mozg: povedencheskie i stryktyrno-fynkcionalnie patterni // Itogi nayki i tehniki. Radiacionnaya biologiya. M.: VINITI, 1987. T.8. 336 s.


3.Davidov B.I., Yshakov I.B., Fedorov V.P. Radiacionnoe porajenie golovnogo mozga. M.: Energoatomizdat, 1991. 240 s.


4.Erohin U.A. Porajenie golovnogo mozga pri raznih stadiyah alkogolnoi bolezni / Vestnik novih medicinskih tehnologii. 2004. N3. S. 56-57.


5.Ilicheva V.N. Sravnitelnaya harakteristika reakcii drevnei kori pri deistvii ioniziryushego izlycheniya i alkogolnoi intoksikacii // Avtoreferat dis. k.m.n. Yaroslavl. 2001. 28 s.


6.Mastrukov A.A., Fedorov V.P. Yadernaya katastrofa veka. Voronej: Naychnaya kniga, 2016. 404 s.


7.Paykov V.S. Izmeneniya golovnogo mozga v doklinicheskoi stadii alkogolnoi bolezni i pri alkogolizme / Narkologiya. 2004. N5. S. 32-36.


8.Postrelko V., Chernii A. Chernobilskaya katastrofa i alkogol: klinika, epidemiologiya i lechenie. LAP LAMBERT Academic Publishing, 2013. 75 s.


9.Sokolov D.A. Stryktyrno-fynkcionalnaya harakteristika staroi kori golovnogo mozga pri alkogolnoi intoksikacii i deistvii ioniziryushego izlycheniya / Avtoreferat dis. k.m.n. Yaroslavl. 2007. 25 s.


10.Yshakov I.B., Fedorov V.P. Rannie izmeneniya integrativnih sistem golovnogo mozga kris pri sochetannom deistvii etanola, i gamma oblycheniya / Med. radiologiya. 1988. T. 33. N 10. S. 50-56.


11.Yshakov I.B., Lapaev V.E., Voroncova Z.A., Doljanov A.Ya. Alkogol i radiaciya (ocherki radiacionnoi narkologii ili radiacionnii Chernobil). Voronej: Istoki, 1998. 248 s.


12.Yshakov I.B., Fedorov V.P. Malie radiacionnie vozdeistviya i mozg. Voronej: Naychnaya kniga, 2015. 536 s.


13.Yshakov I.B., Fedorov V.P. Vozdeistvie faktorov chernobilskoi avarii na psihonevrologicheskii statys likvidatorov-vertoletchikov / Medicinskaya radiologiya i radiacionnaya bezopasnost. 2018. T. 63. N 4. S. 22-32.


14.Fedorov V.P., Shiryaev O.U., Fedorov N.V. Neiromorfologicheskie effekti ostroi alkogolnoi intoksikacii / Sovremennie napravleniya issledovanii fynkcionalnoi mejpolysharnoi assimetrii i plastichnosti mozga: Materiali Vserossiiskoi konferencii (Moskva 2-3 dekabrya 2010 goda). M.: Naychnii mir, 2010. S. 621-624.


15.Fedorov V.P., Shiryaev O.U., Fedorov N.V. Modificiryushee vliyanie etanola na yltrastryktyrnie izmeneniya golovnogo mozga posle oblycheniya / Morfologiya. 2016. T.149. N3. S. 213-214


16.Fedorov V.P., Astashova A.N. Cerebralnie effekti alkogolya pri radiacionnih avariyah / Problemi obespecheniya bezopasnosti pri likvidacii posledstvii chrezvichainih sityacii. 2018. T.1. S. 683-685.


17.Fedorov V.P., Yshakov I.B., Shalnova G.A. Etanol kak vozmojnii modifikator ostrogo radiacionnogo porajeniya mozga // Radiacionnaya biologiya i radioekologiya. 2019. T.59. N 2. S.184-191.


18.Fedorov V.P. Izmeneniya neironov yzla troinichnogo nerva pri ostrom radiacionnom vozdeistvii / Sovremennaya morfologiya: problemi i perspektivi: sbornik trydov naychno-prakticheskoi konferencii s mejdynarodnim ychastiem, ch. 1. Minsk: IVC Minfina, 2019. S. 128-131.


19.Fedorov V.P., Astashova A.N. Rannyaya reakciya afferentnogo neirona na alkogolnyu intoksikaciu / Morfologicheskie nayki i klinicheskaya medicina: materiali Vserossiiskoi naychno-prakticheskoi konferencii. Cheboksari: Chyvashskii yniversitet, 2019. S. 135-138.


20.Shormanov S.V. Stryktyrnie izmeneniya golovnogo mozga cheloveka v ysloviyah ostroi alkogolnoi intoksikacii / Arhiv patologii. 2004. ?4. S. 9-13.


21.Rodriguez S.D., Brar R.K., Drake L.L., Drumm H.E. The effect of the radio-protective agents ethanol, trimethylglycine, and beer on survival of X-ray-sterilized male Aedes aegypti / Parasit Vectors. 2013. V. 18. N 6. P. 211-216.


22.Fyodorov V.P., Ushakov I.B., Shalnova G.A. Ethanol as a Possible Modifier of Acute Radiation Lesions of the Brain / Biology Bulletin, 2019. V. 46, N11. P. 1493-1499.