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Vol. 16, Art. 112 (pp. 1302-1316)    |    2015       

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Perioperative changes microbiocenosis in patients with colon and rectum cancer

S.F. Bagnenko1, A.A. Zakharenko1, A.N. Suvorov2, I.V. Shlyk1, O.A. Ten1, S.R. Dzhamilov, M.A. Belyaev1, A.A. Trushin1, A.S. Natha1, D.A. Zaycev1, K.N. Vovin1, V.A. Rybalcheno1, D.O. Akulichev1

Brief summary

In patients with colorectal cancer showed violations of the colon microbiocenosis, manifested either by a decrease in anaerobic microbiocenosis, or an increase in opportunistic bacteria. Against the background of preoperative preparation, conservative therapy and surgical intervention, the dysbiosis of the colon is progressing. As a result, a sharp increase in the number of saprophyte microbes with a high resistance to drugs is possible. The most famous representative of such microorganisms is the pathogenic strain of Clostridium difficile, often provoking the development of pseudomembranous colitis.


Key words

colorectal cancer, colon dysbiosis, antibiotic-associated diarrhea

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