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Vol. 16, Art. 105 (pp. 1195-1221)    |    2015       

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The basic mechanisms of acute thromboembolism of lower limb ischemia

Soroka V.V., Nohrin S.P., Magamedov I.D., Ryazanov A.N.
Department of vascular surgery, Djanelidze Research Institute of Emergency Medicine

Brief summary

Prevention and treatment of acute ischemia is one of the most actual problems of vascular surgery. Attempts of solving these problems with surgery have been taking place since the end of 19-th century. Restoration of arterial blood flow is well studied nowadays. The technique of reconstructive procedures on different region arteries is created, but there is relatively high quantity of complications and death during postoperative period. Primarily, this is so, because local lesions start systemic reactions. "Local" method of regional blood flow lesion treatment hadn't solved the problem of early and late complications in postoperative period. Further studying of ischemia processes and reperfusion syndrome will help improve treatment results. Studying the components of this problem, its' role in the complication development have not only theoretical but clinical meaning for developing prognostic and treatment programs.


Key words

thrombosis, ischemia, reperfusion, inflammation, microcirculation.

Reference list

1. Amelin A.V. Narysheniya sistemi gemostaza i ih farmakologicheskaya korrekciya / A.V. Amelin, U.D. Ignatov, N.N. Petrishev, M.V. Pchelincev, M.L. Stepanyan. - SPb.: Izdatelstvo SPbGMY, 2000. - 80 s.


2. Barinov E.F., O.N. Sylaeva. Molekylyarnie mehanizmi trombogeneza. // Kardiologiya. -2012. - N12. - s.45-56.


3. Batakov S.S. Lechenie ostroi arterialnoi neprohodimosti y bolnih infarktom miokarda / S.S. Batakov // Angiologiya i sosydistaya hiryrgiya. - 2004. - N2. (Priloj.). - S. 30-31


4. Bilenko M.V. Ishemicheskie i reperfyzionnie povrejdeniya organov / M.V. Bilenko. - M.: Medicina, 1989. - 368 s.


5. Vladimirov U.A. // Biologicheskie membrani i membranoaktivnie soedineniya. - Tashkent: FAN, 1985. - S. 14 - 28.


6. Gaiton A.K. Medicinskaya fiziologiya / A.K. Gaiton, Dj. E. Holl/ Per. s angl.; Pod red. V.I. Kobrina. - M.: Logosfera, 2008. - 1296s.: il.: 21,1 sm. - ISBN 978-5-98657-013-6.


7. Gacyra V.V., Sidorenko A.F. //Yspehi fiziologicheskoi nayki. - 1986. - T.17, N 4. - S. 38 - 56.


8. Gorbenko M.U. Hiryrgicheskoe lechenie ostrih trombozov arterii nijnih konechnostei / Moskva 2009/ Avtoreferat S.141 .


9. Gygyshvili L.L. Retrogradnoe krovoobrashenie pecheni i portalnaya gipertenziya. - M.: Medicina, 1972. - 196s.


10. Djanelidze U.U. Embolektomiya / U.U. Djanelidze, Z.V. Ogloblina // Vestnik hiryrgii i pogranichnih oblastei. - 1926. - T.8, N 24 (chast I). - S. 85-103.


11. Ivanov K.P. Morfometricheskii analiz roli leikocitov v narysheniyah mikrocirkylyacii v kore mozga /K.P.Ivanov, N.N.Melnikova //Morfologiya.- 2003.- t.124.-N6.-s.61-65.


12. Ivashenko V.V. Sindrom vklucheniya v hiryrgii ostroi embologennoi neprohodimosti arterii konechnostei / V.V. Ivashenko // Vestnik hiryrgii - 1983 - N9. - S. 13 - 19.


13. Ivashenko V.V. Ostrie trombozi i embolii biffyrkacii aorti i magistralnih arterii konechnostei y bolnih revmatizmom / V.V. Ivashenko. - Doneck : Zdorove, 1992. - 120 s.


14. Kapelko V.I., Gorina M.S., Novikova N.A. // Metabolizm miokarda. - M., 1983. - S. 45 - 49.


15. Kolchinskaya A.Z. //Patologicheskaya fiziologiya - 1981. - N4. - S.3 - 10.


16. Kohan E.P. Poyasnichnaya simpatektomiya v kompleksnom lechenii obliteriryushih zabolevanii nijnih konechnostei / E.P.Kohan, O.V.Pinchyk // Angiologiya i sosydistaya hiryrgiya. - 1997. - N1. - s.83-92.


17. Kylikov V.U., Semenuk A.V., Kolesnikova L.I. Perekisnoe okislenie lipidov i holodovoi faktor. - Novosibirsk: Nayka, 1988. - 191 s.


18. Lenindjer A. Osnovi biohimii. - M.: Mir, 1985. - T.2. - S. 368.


19. Mayanskii A.N. Ocherki o neitrofile i makrofage /A.N.Mayanskii, D.N.Mayanskii. - Novosibirsk: Nayka, 1989.


20. Metabolizm miokarda: Materiali 1-go sovetsko-amerikanskogo simpoziyma. - M.: Medicina, 1975 - S. 178, 204, 212.


21. Nacionalnie rekomendacii po vedeniu pacientov s zabolevaniyami arterii nijnih konechnostei. Moskva 2013. S 67.


22. Nehaev I.V. Immynokorrigiryushaya terapiya sepsisa /I.V.Nehaev, S.P.Sviridova, O.G.Mazyrina // Infekcii v hiryrgii. - 2004. - T.2. - N3. - s.2-6.


23. Nohrin S.P. Optimizaciya diagnostiki i lecheniya kriticheskoi ishemii nijnih konechnostei y bolnih s visokim hiryrgicheskim riskom. SPb. 2007 Avtoreferat. S. 242.


24. Oksman T.M., Dalin M.V., Kovanov V.V. // Dokl. AN SSSR. - 1971. - T.199, N4. - S.980 - 983.


25. Orlov S.N. // Biomembrani. - Saransk, 1984. - S. 26 - 34.


26. Ostraya ishemiya organov i rannie postishemicheskie rasstroistva: Tezisi dokladov 2-go Vsesouznogo simpoziyma po ostroi ishemii. - M., 1978. - 495s.


27. Petrishev N.N. Tromborezistentnost sosydov / N.N. Petrishev. - SPb.: ANT-M, 1994. - 130 s.


28. Rodoman G.V. Sivorotochnii albymin pri sindrome sistemnoi vospalitelnoi reakcii i poliorgannoi nedostatochnosti /G.V.Rodoman, T.I.Shalaeva, T.V.Dinjinova // Infekcii v hiryrgii. - 2004. - T.2. - N3. - s.12-16.


29. Sabaneev I.F. K voprosy o shve sosydov / I.F. Sabaneev // Rysskii hiryrgicheskii arhiv. - 1895. - N4. - S. 625-639.


30. Savelev V.S. Embolii bifyrkacii aorti i magistralnih arterii konechnostei (klinika, diagnostika, lechenie) / V.S. Savelev, I.I. Zatevahin. - M.: Medicina, 1970. - 167 s.


31. Savelev V.S. Ostraya neprohodimost bifyrkacii aorti i magistralnih arterii konechnostei / V.S. Savelev, I.I. Zatevahin, N.V. Stepanov. - M.: Medicina, 1987. - 304 s.


32. Titov V.N. Obshnost ateroskleroza i vospaleniya: specifichnost ateroskleroza kak vospalitelnogo processa (gipoteza) // Biohimiya. -2000. - N4. - s.3-10.


33. Chazov E.I. Trombozi i embolii v klinike vnytrennih boleznei / E.I. Chazov // Bolshaya medicinskaya enciklopediya / pod red. B.V. Petrovskogo. - M., 1985. - T.25. - S. 299-301.


34. ShiffmanF.Dj. Patofiziologiya krovi/Per. s angl. - M.: ?Izdatelstvo BINOM?, 2009 - 448s.:il.


35. Shlyahto E.V. Oslojneniya infarkta miokarda / E.V. Shlyahto // Neotlojnaya kardiologiya: dostijeniya i perspektivi: Materiali Vseros. naych. konf. - SPb., 1996. - S. 28 - 31.


36. Embologennaya neprohodimost aorti i arterii konechnostei./ A.E Barsykov, M.V. Melnikov. - SPb.: Gippokrat, 2005. - 120 s.


37. Baue A.E. Multiple organ failure, multiple organ dysfunction syndrome, and systemic inflammatory response syndrome. A.E.Baue // Arch. Surg.- 1997.- Vol.132.- N3. - P.703-707.


38. Beard J, Gaines P, Earnshaw J. Management of acut lower limb ischaemia. Vascular and Endovascularsurgery. 4th edition. 2009; 8: 129-146.


39. Beckman J.S., Beckman T.W., et al. Apparent hydroxyl radical production by peroxynitrite implications for endothelial injury from nitric oxide and superoxide. ProcNatlAcadSciUSA 1990; 87: 1620.


40. Bergmeier W., Piffath C.L., Goerge T. The role of platelet adhesion receptor GPI balpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis. Proc Nat AcadSci USA 2006; 103:16 900 - 16 905.


41. Berliner J.A. Atherosclerosis - basic mechanisms: oxidation, inflammation, and genetics. J.A. Berliner, M. Navab, A.M. Fogelman, J.S. Frank, L.L. Demer, P.A. Edwards, A.D. Watson, A.J. Lusis // Circulation. - 1995. - Vol.91. - P. 2488-2496.


42. Bone R.C. Modulators of coagulation: a critical appraisal of their role in sepsis. R.C. Bone // Arch. Intern. Med. - 1992. - Vol.152. - P. 1381-1389.


43. Carlson K.M. Peripartum cardiomyopathy presenting as lower extremity arterial thromboembolism. A case report. K.M. Carlson, J.E. Browning, M.K. Eggleston, R.B. Gherman // J. Reprod. Med. -2000. -Vol.45, N4. -R. 351-353.


44. Cicala C. Linkage between inflammation and coagulation: an update on the molecular basis of the crosstalk. C. Cicala, G. Cirino // Life Sci. - 1998. - Vol.62, N20. - R. 1817-1824.


45. Colman R.W. The role of plasma proteases in septic shock. R.W. Colman // N. Engl. J. Med. - 1989. - Vol.320, N18. - R. 1207-1209.


46. Cowan J.C., Vaughan Williams E.M.// J. molec. Cell. Cardiol. - 1980. - Vol. 12. - P. 347 - 369.


47. Davies B, Braithwaite B.D, Birch PA, et al. Acute leg ischaemia in Gloucestershire. Br J Surg. 1997; 846: 504-8.


48. Del Maestro R.F. An approach to free radicals in medicine and biology. ActaPhysiolScand 1980; 492 (Suppl) : 153.


49. Dillon P.K., Ritter A.B., Duran W.N. Vasoconstrictor effects of platelet-activating factor in the hamster cheek pouch microcirculation: Dose-related relations and pathways of action. Circ Res. 1998; 62: 722.


50. Dormandy J. Acute limb ischemia. J. Dormandy, L. Heeck, S. Vig // Semin. Vasc. Surg. -1999. -Vol.12, N2. - R. 148-153.


51. Duran WN, Milazzo VJ, et al. Platelet-activating factor modulates leukocyte adhesion to endothelium in ischemia-reperfusion injury. Microvasc Res 1996;51: 108-115


52. Duran W.N., Dillon P.K. Acute microcirculatory effects of platelet-activating factor. J Lipid Mediat 1990;2: S 215.


53. Fogarty TJ, Cranleey JJ, et al. A method for extraction of arterial emboli and thrombi. SurgGynecolObstet 1963; 116: 241.


54. Gosselin R.C. Protein C levels in critically ill ICU patients: differences seen between patients with and without sepsis .R.C.Gosselin, D.M. Roach, J.H. King. et al. // J. of Thromb. Haemostasis. 1(l).- 2003.- P. 27-34.


55. Grace P.A. Ischaemia-reperfusion injury. P.A. Grace // Brit. J. Surg. - 1993. - Vol.81. - P. 637-647.


56. Haimivici H. Muscular, renal and metabolic complications of acute arterial occlusions; mionephropathicmetabolic syndrome . H. Haimivici // Surgery. - 1979. - Vol.85. - P. 461-468.


57. Halliwell B, Gutterridge JMC. Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem J 1984; 219:1.


58. Hess M.L., Krause S.M., Greenfild L.J. // J. Thorac. Cardiovasc. Surg. - 1980. - Vol. 80. - P. 293 - 301.


59. Hess M. L., Okabe E., Kontas H.//J. molec.Cell.Cardiol.-1981.- Vol. 13.-P. 767-772.


60. Hirche N., Bissig R., Freidrich R. et al.// Progr. Enzyme and ion-selective electrodes. - Berlin, 1981. - P. 164 - 170.


61. International Society for Heart Research (European section): Meeting, 9th, Abstracts.-J.Molec. Cell.Cardiol.-1988.- Vol.20.- Suppl. 5.- 89 p.


62. Jarasch E.D., Grund C., et al. Localization of xanthine oxidase in mammary gland epithelium and capillary endothelium. Cell 1981; 25: 67.


63. Kim P.K. Inflammatory responses and mediators. P.K. Kim, C.S. Deutschman // Surg. Clin. North. Am. - 2000. - Vol.80, N3. - P. 885-894.


64. Klinische Angiologie I Hrsg.: Horst Rieger ; Werner Schoop. UnterMitarb. von A. L Strauss, A. Scheffler, G. Driessen - Paris ; Santa Clara ; Singapur ; Tokio : Berlin ; Heidelberg ; New York; Barcelona ; Budapest ; Hongkong ; London ; Mailand ; Springer,1998; 1420


65. Lorant D.E., Patel K.P., et al. Coexpression of GMP - 140 and PAF by endothelium stimulated by histamine or thrombin: A juxtacrine system for adhesion and activation of neutrophils. J Cell Biol 1991; 115: 223.


66. Margarson M.P. Effects of albumin supplementation on microvascular permeability in septic patients /M.P. Margarson, N.C. Soni // J.Appl. Physiol. - 2002. - Vol. 92. - N5. -P.2139-2145


67. Markewitz A. Alterations of cell - mediated immunity following cardiac operations: clinical implications and open questions. A. Markewitz, W. Lante, A. Franke [et al.] // Shock. - 2001. - Vol.16, Suppl.1. - P. 10-15.


68. Mayhang W.G. Role of nitric oxide in leukotriene C4-induced increases in microvascular transport. Am J Physiol 1993; 265: H409-H414.


69. McEver R.P., Bechstead J.H., et al. GMP-140, a platelet granule membrane protein, is also synthesized by vascular endothelial cells and is localized in Weibel-Palade bodies. J Clin Invest 1989; 84: 92-99.


70. Menger M.D. Buflomedil hydrochloride attenuates tourniquet - induced microvascular reperfusion injury in striated muscle / M.D. Menger, D. Steiner, S. Pelikan, K. Messmer // International Journal of Microcirculation. - 1994. - Vol.14, N5. - P. 296-302


71. Menger M.D. Role of oxygen radicals in the microcirculatory manifestations of postischemic injury / M.D. Menger, H.A. Lehr, K. Messmer // Klin. Wochenschr. - 1991. - Vol.69, N15. - P. 1050-1055.


72. Mosny E, Dumont J. Emboliefemorale au coursd un restrecissement mitral pur. Arteriotomie. Guerison. Bull Acad Med (Paris) 1911;66: 358.


73. Mullane K.M., Read N., Salmer J. A. et al.//J. Pharmacol. Exp. Ther.- 1984.- Vol.228.-P.510-522.


74. Murray DWG. Heparin in thrombosis and embolism. Br J Surg 1940; 27:567.


75. Nohl H.// FEBS?Lett.-1987.- Vol.214.-P.269-273.


76. Oxidative stress / Ed. H. Sies. - London: Academic Press. - 1985. - 507 P.


77. Paul J, Bekker AY, Duran WN. Calcium entry blockade prevents leakage of macromolecules induced by ischemia-reperfusion in skeletal muscle. Circ Res 1990; 66:1636.


78. Romson J. L., Hook B. G., Kunkel S. et al.// Circulation.- 1983.- Vol.67.- P. 1016-1023.


79. Rutherford?s vascular surgery / [edited by] Jack L. Cronenwett, K. Wayne Johnston.?Eighth edition.Copyright ? 2014, 2010, 2005, 2000, 1995, 1989, 1976 by Saunders, an imprint of Elsevier Inc.


80. Smith JK, Grisham GB, et al. Free radical defense mechanisms and neutrophil infiltration in postischemic skeletal muscle. Am J Physiol 1989; 256: H789-H793


81. Suval W.D., Hobson R.W. II, et al. Assessment of ischemia reperfusion injury in skeletal muscle by macromolecularclearance. J Surg Res 1987; 42: 550-559.


82. Suval W.D., Duran W.N., et al. Microvassular transport and endothelial cell alternations precede skeletal muscle damage in ischemia-reperfusion injury. Am J Surg 1987; 154:211-218.


83. Yasuhara H, Hobson RW II, et al. A new model for studying ischemia-reperfusion injury in the hamster cheek pouch. Am J Physiol 1991;261: H1626-1629


84. Zimmerman G.A., McIntyre T.M., et al. Endothelial cellassociation platelet-activating factor: a novel mechanism for signaling intercellular adhesion. J Cell Biol 1990;110: 529.