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Vol. 15, Art. 41 (pp. 511-518)    |    2014       

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Etiology of bacteremia and sepsis in patients with hematological malignancies

Schetinkina E.E., Burylev V.V., Kaytandzhan E.I., Stizhak N.P., Bessmeltsev S.S., Chebotkevich V.N.

Russian Research Institute of Hematology and Transfusiology, St. Petersburg, Russia

Brief summary

The article presents the results of a study of etiology bacteremia in patients with hematological malignancies during the period 1991-2012. Based on the study 4742 blood samples it was shown that the frequency of detection of bacteria is 10.4%. The predominance of Gram-positive bacteria was demonstrated among pathogens detected in the bloodstream. It is shown that the development of bacteremia were significantly more frequently occurs on the background of the detection of cytomegalovirus and the Epstein-Barr virus genomes. In recent years there has been increase the frequency of micromycetes detection in the blood of patients with hematological malignancies. The authors indicate the need of development molecular biological methods for earlier diagnosis of bloodstream bacterial infections.


Key words

infectious complications, sepsis, bacteremia, hemoblastosis

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