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Vol. 15, Art. 4 (pp. 24-32)    |    2014       

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Experience of application of remestip in the treatment of proliferative processes of myo- and endometrium

Novikov, E.I.(3) , Benyuk, VA (2), Vinyarski AM (1), Goncharenko V.N.(1),
Silaeva E.A.(2)

1 Centre total gynecology, gynecologic endocrinology and reproductive medicine. Clinical hospital "Feofania", Kiev
2 Department of gynecology № 3 National medical University by A.A. Bogomolets. Kiev
3 Saint-Petersburg research Institute of emergency medical aid of the name
of I.I. Dzhanelidze

Brief summary

Synthetic hormone similar posterior pituitary vasopressin - remaster, calling expressed vasoconstrictive effect by raising the tone smooth muscle vascular wall in arterioles, veins and venules, leads to a decrease in the bloodstream smooth muscular organs (including the uterus), without reducing the smooth muscle fibers. This is especially important when performing intrauterine manipulation - the removal of polyps of the endometrium, the submucous myomatous nodes by hysteroresectoscopy. Research results of efficiency using of remestip showed at a hysteroresectoscopy in complex treatment of good-quality hyperplastic processes endo - and a myometrium. The study was carried out in practices in the two study groups of patients: I - experienced and II - control. The results showed high efficiency of the remestip: significant reduction intraoperative blood loss, duration of operation, the operating expenses of the material in comparison with the control group.


Key words

remestip, hysteroresectoscopy, polyps of the endometrium, submucous myomatous nodes, intraoperative blood

Reference list

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2. Savickii G.A., Savickii A.G. Mioma matki: problemi patogeneza i patogeneticheskoi terapii.-SPb.-2000.


3. Amant F., Dorfling C.M., de Brabanter J., et al. A possible role of the cytochrome P450c17alpha gene (CYP17) polymorphism in the pathobiology of uterine leiomy- omas from black South African women: a pilot study. Acta Obstet Gynecol Scand 2004; 83(3): 234-9.


4. Broder M.S., Bovone S. Improving treatment outcomes with a clinical pathway for hysterectomy and myomectomy. J Reprod Med 2002; 47(12): 999-1003.