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Vol. 13, Art. 3 (pp. 25-37)    |    2012       

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Clinical approbation of emergency adjuvant hyperthermic intraperitoneal chemotherapy in complicated colorectal cancer

Djanelidze Research Institute of Emergency Medicine, Saint Petersburg, Russia

Brief summary

The paper presents the results of clinical trials of adjuvant treatment of intraoperative hyperthermicintraperitoneal chemotherapy, which was conducted in an emergency operating patients with complicated forms of colon cancer. Our studies showed the absence of express and/or irreversible changes in the basic life-saving organ systems in-patient coefficients when performing surgery, followed by the implementation of adjuvant intraoperative intraperito-nealhyperthermicchemoperfusion on the complicated forms of colorectal cancer. It is also shown positive effects of adjuvant intraperitonealhimiogipertermicheskoy perfusion in long-term results after radical surgery in the operating conditions of emergency patients with complicated colorec-tal cancer.


Key words

colorectal cancer, peritoneal carcinomatosis, adjuvant hyperthermicintraperitoneal chemotherapy.

Reference list

1. Moiseenko V.M., Orlova R.V. Aduvantnoe lechenie bolnih rakom obodochnoi kishki // Prakticheskaya onkologiya. – 2000. – № 1. – S. 19–23.


2. Orlova R.V., Chybenko V.A. Aduvantnaya terapiya zlokachestvennih novoobrazovanii jelydochno-kishechnogo trakta // Prakticheskaya onkologiya. – 2007 – T. 8, № 3. – S. 127–133.


3. Jacquet P., Zhu B.W., Sugarbaker P.H. et al. Peritoneal carcinomatosis from intraabdominal malignancy: natural history and new prospects for management // Acta. Belg. Chir. – 1994. – Vol. 94. – P. 191–197.


4. Osinskii D.S., Bejar A., Chernii V.A. i dr. Vnytribrushnayahimiogipertermicheskaya perfyziya i citoredyktivnaya operaciya v lechenii bolnih karcinomatozom brushnoi polosti // Onkologiya. – 2003. – T. 5, № 1. – S. 55–62.


5. De Roover A., Detroz B., Detry O. et al. Prognostic analysis of clinicopathologic factors in 49 patients with diffuse malignant peritoneal mesothelioma treated with cytoreductive surgery and intraperitonealhyperthermic perfusion // Ann. Surg. Oncol. – 2006. – Vol. 13, № 2. – P. 229– 237.


6. Scaringi S., Kianmanesh R., Sabate J.M. et al. Advanced gastric cancer with or without peritoneal carcinomatosis treated with hyperthermicintraperitoneal chemotherapy: a single western center experience // Eur. J. Surg. Oncol. – 2008. – Vol. 34, № 11. – P. 1246–1252.