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Vol. 12, Art. 55 (pp. 665-678)    |    2011       

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Oxidative stress in the formation during hypoxia of severe bronchial asthma

N.B.Karmen, M.A.Abdullaeva, L.V.Tokareva

Brief summary

Investigated the structural and functional state of erythrocyte membranes (as cell model) in severe bronchial asthma. Shown that the disease is accompanied by marked changes in the structure and function of membranes caused by hyperactivation of lipid peroxidation. Damage to the cell membrane is the primary mechanism for the formation of a mixed hypoxia in bronchial asthma.


Key words

bronchial asthma, hypoxia, membrane, erythrocyte, lipid peroxidation

Reference list

1. Chychalin A.G. (red.) Globalnaya strategiya lecheniya i profilaktiki bronhialnoi astmi (peresmotr 2006 g.). M.: Atmosfera, 2007. – 104 s.


2. Cunningham J. Socioeconomic status and self-reported asthma in Indigenous and non-Indigenous Australian adults aged 18-64 years: analysis of national survey data// Int. J. Equity Health. – 2010. - v. 10. - № 9. – P. 18.


3. Navaratnam P., Friedman H., Urdaneta E. The impact of adherence and disease control on resource use and charges in patients with mild asthma managed on inhaled corticosteroid agents// Patient Prefer Adherence. – 2010. - v. 24. - № 4. – P. 197-205.


4. Rosychuk R.J., Voaklander D.C., Klassen T.P. et al. Asthma presentations by children to emergency departments in a Canadian province: a population-based study// Pediatr. Pulmonol. – 2010. - v. 45. - № 10. – P. 985-992.


5. Windt R., Glaeske G. Effects of a german asthma disease management program using sickness fund claims data// J. Asthma. – 2010. - v. 47. - № t6. – P. 674-679.


6. Chychalin A.G. Tyajelaya bronhialnaya astma//Rysskii Medicinskii Jyrnal. – 2000. - t.8. - № 12. – S. 482-486.


7. Ennight P.L., Lebowitz M.D., Cockroft D.W. Phisiologic measures: Pulmonary function test//Ann. J. Respir. Crit. Care Med. – 1994. – v. 149. – P. S9-S18.


8. Leiner G.C., Abramowitz S., Small M.J. et al. Expiratory peak flow rate. Standard values for normal subjects. Use as a clinical test of ventilatory function// Am. Rev. Respir. Dis. – 1963. – v. 88. – P. 644-651.


9. Stalnaya I.D., Gorishvili T.D. Metod opredeleniya malonovogo dialdegida s pomoshu tiobarbityrovoi kisloti//Sovremennie metodi v biohimii. M.: Medicina, 1977. - S. 66-68.


10. Stalnaya I.D. Metod opredeleniya dienovoi konugacii nenasishennih kislot//Sovremennie metodi v biohimii. M.: Medicina, 1977. - S. 63-64.


11. Bidlack W.R., Dyel A.L. Damage of microsomal membrane by lipid peroxidation//Lipids. - 1959. - v. 8. - № 4. - P. 177-182.


12. Fried R. Enzymatic and non- enzymatic assy of superoxide dismutase//Biochem. -1975. – v. 87 - P. 657-666.


13. Minami M., Yoshikama H. A simplitied method of superoxide dismutase activity for clinical use//Clin. Chim. Acta. - 1979. - v. 92. - № 3. - r. 337-342.


14. Koroluk M.A., Ivanova L.I., Mairova I.G. i dr. Metod opredeleniya aktivnosti katalazi.//Laboratornoe delo. - 1988. - № 1. - S. 16-19.


15. Luce J.M. Acute lung injuri and acute respiratory distress syndrom.//Crit. Care Med. – 1998. – v. 26. - № 2. – r. 369-376.


16. Kolb V.G., Kamishnikov V.S. Spravochnik po klinicheskoi himii. Minsk: Belarys, 1982. - 256 s.


17. Stepyro I.I., Chaikovskaya N.A., Solodynov A.A., Arcykevich A.N. Obrazovanie NO• v processe okisleniya ferrohrom gemoglobina nitritom//Biohimiya. – 1997. – t.62. - № 9. - S. 1122-1129.


18. Vnykov V.V., Milutina N.P., Nikolaeva E.E. i dr. Vliyanie ynitiola na intensivnost POL v krovi i stryktyrno-fynkcionalnie svoistva eritrocitov eksperimente i y bolnih IBS pri GBO-terapii. Rostov-na-Dony, 1995. - 24 s.


19. Misra H.P., Fridovich I. The role of superoxide anion in the autooxidation of epinephrine and simple assay for SOD.//J. Biol. Chem. - 1972. - v. 247. - r. 3170-3175.


20. Kolchinskaya L.I., Lishko V.K., Malisheva M.K. Izychenie vzaimodeistviya Na+, K+ - ATF-azi eritrocitov s sybainom, vliyanie acetilfosfata//Biohimiya. - 1976. - № 3. - S. 933-938.


21. Bligh E., Dyer W.J. Rapid method of total lipid extraction fnd purification//Can. Biochem. Physiol. - 1959. - v. 37. - № 8. - P. 911- 912.


22. Vladimirov U.A., Dobrecova G.V. Flyorescentnie zondi v issledovanii biologicheskih membran. M., Nayka, 1980. - 320 s.


23. Lichev V.G. Diagnostika i lechenie disseminirovannogo vnytrisosydistogo svertivaniya krovi. M.: «Medicinskaya kniga», 2001. – 192 s.


24. Ryazanceva N.V. Patofiziologiya eritrocitov pri psihicheskih rasstroistvah: Avtoreferat diss. … d.m.n. Tomsk, 2001. – 43 s.


25. Milutina N.P., Ananyan A.A., Lyshkaeva O.A. i dr. Perekisnoe okislenie lipidov i aktivnost antioksidantnih fermentov krovi, stryktyrno-fynkcionalnie svoistva eritrocitov pri ateroskleroze, ishemicheskoi bolezni serdca, infarkte miokarda. Rostov-na-Dony, 1995. - 23 s.


26. Sergeev P.V., Galenko-Yaroshevskii P.A., Shimanovskii N.L. Ocherki biohimicheskoi farmakologii. M., RC «Farmedinfo», 1996. – 384 s.


27. Vladimirov U.A. Svobodnie radikali i antioksidanti//Vestnik Rossiiskoi AMN, 1998. - № 7. – S.43-51.


28. Heckers H., Platt D., Brosche T., Summa J.D. The effect of different fat supplemented diets on the erythrocyte ghosts and plasma lipid composition of geriatric subjects//Arch. Gerontol. Geriatr. – 1986. - v. 5. - №2. – P. 83-95.


29. Grigorev E.V., Chyrlyaev U.A. i dr. Diagnosticheskie vozmojnosti ocenki povrejdeniya endoteliya i svyazi s endogennoi intoksikaciei pri peritonite// Kriticheskie i terminalnie sostoyaniya: patofiziologiya i terapiya. M., 2002. – S. 32.


30. Petrishev N.N. Patogeneticheskoe znachenie disfynkcii endoteliya//Omskii naychnii vestnik. - 2005.- № 3. – S. 20-23.


31. Semchenko V.V., Voinov A.U., Golevcova E.Sh. i dr. Gemostaz i sosydistii endotelii pri cherepno-mozgovoi travme. Omsk-Nadim, 2003. – 168 s.