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Vol. 11, Art. 20 (pp. 254-267)    |    2010       

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Erythropoetin in the integrated therapy of b-thalassemia and its influence on the basic indicators of ferroporphyrin complex

Baytayeva D.A., Bessmeltsev S.S.*

Azerbaijan Institute of Scientific-Researching of Hematology and Transfuziology
*- Russian Research Institute of Hematology and Transfusiology

Brief summary

In conditions of homozygotus and intermediary forms of ?-thalassemia an analysis of the results of influence of epoetin-? (eprex) on the development of anemia and on the basic indicators of ferroporphyrin complex using the advanced methods of study. The curative effect was stated to depend on the selected drug dose and on the liver's functional status. Unlike in case of the homozygotus ?-thalassemia, with the intermediary form of the disease it is recommended to prescribe Eprex in combination with hydroxyurea as an alternative to hemotransfusions.


Key words

erythropoetin, soluble transferrin receptor, zinc protoporphyrin, hemosiderosis, coproporphyrin, protoporphyrin, serum iron, serum ferritin.

Reference list

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